Program

Hochschule trifft Industrie 2024 

Olivier Loiseleur (Syngenta), Patrick Isenegger (Syngenta), Franziska Thomas (Heidelberg University), Adrián Gómez Suárez (Wuppertal University), Golo Storch (Technical University of Munich)

Programm as PDF.

Wednesday, September 25th 2024

Until 11:30 am: Check-In at Hotel Goldener Knopf, Rathausplatz 9, 79713 Bad Säckingen

11:30   Walk from Hotel to Syngenta

12:00   Registration

12:30   Lunch/Get-together 

13:30   Welcome

Session 1 (Chair Michel Rickhaus)

13:35   Jaspreet Kaur, Barham Lab 

Autophotocatalysis: unveiling a self-synthesizing library of generally applicable reductive organophotoredox catalysts
14:00   Oleg Borodin, Boehringer Ingelheim Pharma GmbH & Co. KG
Illuminating Medicinal Chemistry: Exploration of the Parameter and Chemical Space in Photoredox C(sp2)-C(sp3) Cross-Coupling Reactions

14:25   Coffee Break

Session 2 (Chair Dmitry Katayev) 

14:40   Yu Zhang , Jessen-Trefzer Lab 

Engineering encapsulins for targeted enzyme prodrug therapy in cancer treatment

15:05   Timo Heinrich, Merck KGaA

TEAD Selectivity Investigations – A Structure Guided Approach

Session 3 (Chair Adrián Gómez Suárez)

15:30   Subrata Patra, Katayev Lab 

Molecular Design Using Catalytic Radical Nitration

15:55   Stefan Eissler, Bachem AG

Large-Scale Peptide Manufacturing at Bachem

16:20   Coffee Break 

Session 4 (Chair Cathleen Zeymer)

16:35   Marius Werner, Thomas Lab

Engineering MHC recognition and biological kinetics of peptides by novel chemistry

17:00   Jan Schütz, DSM-Firmenich

Advancing Flow Chemistry in the Fine Chemical Industry: A Photocatalytic Perspective

17:25   Tim Langschwager, Storch Lab

Photocatalytic addition reactions of masked functional groups to dehydroalanines by flavin catalysis

18:00   Walk from Syngenta to Hotel

19:00   Dinner 

Thursday, September 26th 2024

8:30      Walk from Hotel to Syngenta

9:00     Rebecca Buller, Zurich University of Applied Sciences

Engineering protein catalysts for synthetic applications

9:50     Coffee Break

Session 5 (Chair Jola Pospech)

10:05   Benedikt Nißl, Konrad Lab

A biomimetic synthesis of tetrodotoxin enabled by high-throughput C-H functionalization screenings

10:30   Denis Gribkov, Syngenta Crop Protection

PLINAZOLIN® technology. Striving for sustainable future

Session 6 (Chair Agnieszka Nowak-Król)

10:55   Jannik Thaens, Pospech Lab 

            C−H bond oxygenation through photo-mediated oxidative radical-polar cross-over

11:20   Hergen Schultze and Bernd Schäfer, BASF SE

Artificial Intelligence for Reaction Optimization 

11:45   Lunch

Session 7 (Chair Johannes Wahl)

13:00   Patrick Geppert, Nowak-Król Lab 

Azaborole-containing diarylethene photoswitches

13:25   Claudio Bomio, Novartis 

Adventures in Atropisomerism

Identification and Optimization of a Novel Class of KRASG12C Inhibitors: Discovery of JDQ443

13:50   Sebastian Govaerts, Gómez Suárez Lab

Synthesis of C(sp3)-rich Amine-Containing Building Blocks via Electrophilic (Spiro)cyclopropanes

14:20   Site Visit (#1)

15:00   Site Visit (#2) 

16:30   Poster Session

18:00   Dinner

20:00   Helma Wennemers, ETHZ, Switzerland

Asymmetric Peptide Catalysis – From Simple to Complex Environments

22:15    Walk from Syngenta to Hotel

Friday, September 27th 2024

8:30      Walk from Hotel to Syngenta

Session 8 (Chair David Konrad)

9:00     Marlene Arnold, Wahl Lab 

Synthesis and application of axially chiral cyclobutanone oxime esters for the preparation of chiral cyclopropanes

9:25     Elisabeth Speckmeier, Sanofi

High-Throughput Approaches in Modern Medicinal Chemistry

Session 9 (Chair Claudia Jessen-Trefzer)

9:50     Srishti Ballabh Bahukhandi, Zeymer Lab 

Expanding the enzymatic photoredox repertoire with PQQ-dependent dehydrogenases

10:15   Paolo Tosatti, F. Hoffmann-La Roche

Second-generation manufacturing process of Migoprotafib

10:40   Coffee Break

Session 10 (Chair Joshua Barham)

10:55   Ludmilla Sturm, Rickhaus Lab 

Unlocking Supramolecular Synthesis? The Strategic Design of Curved Polyaromatics For Self-Assembly

11:20   Dr. Frank Wetterich, Bayer AG

         Development principles for Pharmaceutical Drug Substance Manufacturing with Rogaratinib as case study

11:45   Poster Prize HTI 2024

12:00   HTI 2026 Announcement and Closing Remarks 

12:15   Lunch to Go 

12:30   Walk from Syngenta to Hotel